• Mechanisms of oxytocin receptor downregulation
  • Identifying positive modulators of the oxytocin receptor
  • Role of hypercholesterolemia in myometrial contractility
  • Role of S1P-HDL in myometrial contractility

Ex vivo myometrial contractility in response to oxytocin

We utilize mouse models, cells lines, and primary human tissue/cells to study the pathways involved in myometrial contractility.
Oxytocin receptor desensitization